A Comprehensive Literature Review on Managing Systemic Lupus ...
idiopathic pulmonary hypertension treatment :: Article Creator New Target Identified For Pulmonary Hypertension Treatment Histone H3 lysine 9 (H3K9) acetylation and SPHK2 (sphingosine kinase 2) expression show a potential correlation in pulmonary arterial hypertension (PAH) patients' lungs. A, Representative immunoblot probed for acetyl-H3K9 (Ac-H3K9), total H3, tubulin, and Ponceau S staining in protein lysates of human idiopathic pulmonary arterial hypertension (iPAH: type of group 1 pulmonary hypertension [PH]) lung or failed donor lung (FDL) tissue specimens and ( B) quantitation of Ac-H3K9/total H3, n=19 to 20. C, Quantitation of Ac-H3K9/tubulin in protein lysates of human iPAH (n=11) or FDL (n=9). D, SPHK2 expression levels normalized against 18S rRNA in iPAH lung and FDL tissues. N=20. E, Representative immunoblot probed for SPHK2 and tubulin in protein lysates of human iPAH (type of group 1 PH) lung or FDL tissue specimens and ( F) quan...