Evaluation and Management of Pulmonary Hypertension in Noncardiac Surgery: A Scientific Statement From the American Heart Association



pulmonary hypertension and portal hypertension :: Article Creator

AI Breakthrough In Pulmonary Hypertension Diagnosis: CHEST 2024

PULMONARY hypertension (PH) is a progressive and potentially fatal condition that can go undetected until it reaches advanced stages. Current diagnostic methods, such as transthoracic echocardiography (TTE), lack both sensitivity and specificity and may require invasive right heart catheterization to confirm a diagnosis. However, a groundbreaking study presented at the CHEST Annual Meeting 2024 in Boston, held from October 6 to 9, introduces a multimodal fusion model (MMF-PH) that could transform the detection of PH.

This innovative deep learning algorithm integrates data from electronic health records, including chest radiographs, ECG, demographics, and TTE findings, to deliver more accurate results than traditional TTE screening methods alone. The study found that MMF-PH demonstrated superior diagnostic performance across various patient groups, showing great promise for clinical use.

The research analyzed a dataset of 4,576 patients with unconfirmed but suspected PH at Beijing Fuwai Hospital, China, between 2019 and 2021. Of these, 2,451 cases were confirmed using right heart catheterization. The algorithm was rigorously trained and validated using both retrospective and prospective data, including external datasets from other medical institutions.

Dr. Zhihua Huang, from Chinese Academy of Medical Sciences and Fuwai Hospital said of the algorithm: "This multimodal deep learning algorithm enables early, accurate identification of pulmonary hypertension and its subtypes, potentially reducing the need for invasive procedures. It has the potential to significantly improve patient management and outcomes while reducing healthcare costs."

With its potential to improve early diagnosis and guide personalized treatments, the MMF-PH algorithm could revolutionize the clinical management of pulmonary hypertension, offering a less invasive, AI-driven solution.

Reference: Huang Z et al. Revolutionizing pulmonary hypertension detection: a multicenter study on a comprehensive multimodal deep learning approach. Abstract 4029. CHEST Annual Meeting. October 6-9, 2024.

Anaya MalikAMJ


Hypertension News

July 19, 2024 — When it comes to community hypertension interventions, a new study found that pharmacists and community health workers had the best success in lowering blood pressure. These findings support the idea ...

June 6, 2024 — People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study suggests that engaging in vigorous physical activity more than once a week can lower ...

June 5, 2024 — Adolescents with elevated blood pressure and arterial stiffness may experience poorer cognitive functions, according to a recent study. Young people with higher blood pressure performed worse, ...

May 15, 2024 — New research finds a link between common medications and life-threatening ...

May 2, 2024 — Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading ...

Apr. 30, 2024 — Researchers have discovered over a hundred new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure. In total, over 2,000 independent ...

Apr. 11, 2024 — A drug approved to treat pulmonary arterial hypertension may be effective at managing hypertension and end-organ damage in patients with sickle cell disease, according to a new study. An early phase ...

Apr. 11, 2024 — Health researchers identify patients at risk for preventable death in the year after ...

Mar. 27, 2024 — Sleeping fewer than seven hours is associated with a higher risk of developing high blood pressure over time, according to a new ...

Mar. 20, 2024 — Using data from both mice and humans, a research team has found that a cell surface protein that senses odors and chemicals may be responsible for -- and help explain -- male/female differences in ...

Feb. 21, 2024 — Raised blood pressure has been the leading risk factor for death in Australia for the past three decades, according to a new study. It is also the main contributor to deaths from cardiovascular ...

Feb. 12, 2024 — The replacement of regular salt with a salt substitute can reduce incidences of hypertension, or high blood pressure, in older adults without increasing their risk of low blood pressure episodes, ...

Feb. 5, 2024 — Weight loss medication reduced both day and nighttime blood pressure levels, finds new ...

Feb. 5, 2024 — Bariatric surgery is more effective in controlling hypertension rates, or high blood pressure, in people with obesity and uncontrolled high blood pressure compared to blood pressure medication alone, ...

Jan. 10, 2024 — Researchers uncovered a fundamental mechanism that controls the body's response to limited oxygen and regulates blood vessel disease of the ...

Jan. 10, 2024 — Outdoor humidity and temperature levels during pregnancy could affect the future blood pressure of the unborn child, according to new ...

Jan. 5, 2024 — A new study unlocks the secrets of how high blood pressure (hypertension) fuels the progression of arterial ...

Dec. 13, 2023 — Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs ...

Dec. 12, 2023 — Researchers have found an increased need for urgent dialysis and a rising mortality rate in people hospitalized for dangerously high blood pressure. Younger people needed more dialysis and leaner ...

Dec. 6, 2023 — Spouses or partners in heterosexual relationships may have high blood pressure that mirrors one another, finds new, multinational ...


Breakthroughs In Pulmonary Disease, Advancements In PE Management At CHEST 2024

One of the key highlights was the discussion of Pulmonary Embolism Response Teams (PERT), addressing controversies in PE management and focusing on personalized, patient-centered care.

The CHEST 2024 annual meeting brought together over 6000 to 8000 pulmonologists and researchers to share cutting-edge developments in pulmonary disease, pulmonary embolism (PE), and pulmonary hypertension. One of the key highlights was the discussion of Pulmonary Embolism Response Teams (PERT), addressing controversies in PE management and focusing on personalized, patient-centered care.

Parth Rali, MD, and Krunal Patel, MD from Temple University, emphasized the importance of tailoring treatment based on individual needs with a close look at recent clinical trials in both pulmonary hypertension and PE.

Clinical trials were another recurring theme throughout the conference. Presentations reviewed lessons learned from recent years across pulmonary conditions such as pulmonary vascular disease and explored both positive and negative trial outcomes, setting the stage for advancements in the 2 few years. For institutions like Temple Lung Center, there is a strong push to increase clinical trial participation and bring innovative treatments to more patients.

Beyond pulmonary vascular disease, chronic obstructive pulmonary disease (COPD) emerged as a significant focus, with discussions on the future of its treatment. After decades of relying on inhaler therapies, Jonathan Kurman, MD, Medical College of Wisconsin, Froedtert Hospital, showcased new pharmacologic and nonpharmacologic interventions that promise to transform the standard of care for patients with COPD. Biologics and precision medicine are expected to play a crucial role, offering more personalized treatment options based on patients' phenotypes and genotypes.

In addition to major disease advancements, Zeina Morcors, MD, Staten Island University Hospital, praised the tailored learning opportunities provided. Sessions on sepsis, pregnancy-related embolism, and asthma offered practical knowledge to apply in daily hospital settings. The event also featured simulation experiences, case report presentations, and interactive discussions with global experts.

Sleep medicine also gained attention at CHEST 2024. Tetyana Kendzerska, MD, Division of Respirology, University of Ottawa, presented new research on the relationship between sleep-disordered breathing and mental health conditions, particularly among marginalized populations. She highlighted gaps in sleep study follow-up care, especially for inpatients, and emphasized the need to improve access to sleep therapy.

A final critical takeaway from the conference was the acknowledgment of racial disparities in pulmonary care, brought to light by data presented by Cesar Davila-Chapa, MD, University of Nebraska Medical Center. These inequities continue to affect patient outcomes and hospitalizations, underscoring the importance of addressing social determinants of health in future research and clinical practice.

The CHEST 2024 annual meeting successfully bridged past, present, and future advancements, providing valuable insights and shaping the future of pulmonary care.





Comments

Post a Comment

Popular posts from this blog

Roseola vs. measles rash: What is the difference? - Medical News Today

Image
Roseola and measles are two different diseases that present with a high fever and a rash. They are both most commonly seen in childhood, although measles can affect people of any age, and roseola in adults is very rare. While both diseases share similarities, there are distinguishing factors, such as how the symptoms present and the disease progression. Read on to find out the difference between roseola and measles rashes. Roseola, also known as roseola infantum, sixth disease, or exanthema subitum, is a viral infection that typically affects children. The human herpesvirus 6 (HHV-6) or human herpesvirus 7 (HHV-7) causes roseola. The disease is spread through tiny respiratory droplets that people either breathe in or pick up from surfaces they touch. This disease usually presents in children between the ages of 6–12 months . Children who have this disease experience a high fever, followed by a pink or red rash. Roseola is a self-limiting viral illness, meaning it will typically go awa...
Read more

Athlete's foot: Symptoms, types, causes, treatment, prevention - Insider

Image
Athlete's foot is a fungal infection that causes itchy, flaky skin between toes and on foot soles. You may also experience foul-smelling feet and changes in skin color depending on what type you have. You should start to feel relief about two weeks after starting treatment. Visit Insider's Health Reference library for more stories. Athlete's foot, also known as tinea pedis, is a type of fungal infection called ringworm that affects the feet. It occurs most commonly between the toes or on the soles of the feet. Athlete's foot is quite common and is estimated to affect 3%-15% of people Contrary to the name, you don't have to be an athlete to contract it. The name came about because it is commonly caught and spread in places athletes frequent like gyms and locker rooms.  But the fungus thriv...
Read more

Managing Atrial Fibrillation in Patients With Heart Failure and Reduced Ejection Fraction: A Scientific Statement From the American Heart Association

Image
causes of precapillary pulmonary hypertension :: Article Creator Long-term Oxygen Therapy Improves Exercise Capacity In PH Long-term oxygen improves exercise capacity in people with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH), a study suggests. Twelve weeks of supplemental oxygen led to a significant and clinically relevant improvements in exercise capacity, as assessed with the six-minute walking distance test (6MWD), by 42 meters (about 138 feet) over the distances walked at start of the study, "Long-term oxygen therapy in precapillary pulmonary hypertension — SOPHA study," which was published in Scientific Reports. PH is marked by high blood pressure in the pulmonary arteries, the blood vessels that transport blood from the heart to the lungs. Precapillary PH includes PAH, where blood pressure increases due to the narrowing of pulmonary arteries, along with CTEPH, a rare form of p...
Read more