Poliomyelitis

Meningitis refers to inflammation around the brain and spine, often due to viral or bacterial infection. The infection causes swelling in the meninges, which are thin layers of tissue around the brain and spinal cord. If untreated, meningitis can be life threatening. Pediatric meningitis describes the disease's effects in infants, children, and teens. Meningitis can occur in people of all ages, but newborns and people with weakened immune systems are at an increased risk. Two key vaccines, MenB and MenACWY, protect against strains of bacterial meningitis, the most dangerous kind. The Centers for Disease Control and Prevention (CDC) recommends these vaccines for all kids 11 to 12 years old, with a booster later. They also recommend the Hib vaccine for all kids under 5 years old. This vaccine has been very effective at reducing meningitis mortality rates in children. We'll go over how to recognize the signs of meningitis in different age groups, what treatment methods are avail...

At the end of December of last year, the Omicron variant had been reported in most parts of the country. Since its emergence, the virus has spread more rapidly than the original SARS-CoV-2 virus. Therefore, the CDC suspects that anyone with Omicron can spread the virus, regardless of their vaccination status.   In spite of this, COVID vaccines have proven to protect against severe illness, hospitalizations, and even death. Even so, breakthrough infections can still occur and cause symptoms.  One unusual symptom that has been linked to Omicron has stood out in particular. This surprising symptom can inflict havoc on the eyes and might be an early indicator that someone has been infected with COVID-19. COVID-19 And Your Eyes Among the most common complaints of those with omicron are cough, sore throat, fever, or loss of taste or smell. However, some patients also are plagued with something more unusual: itchy eyes. Conjunctivitis, also known as pink eye...

Trends in some regions are clear, but insect biology, climate quirks, and public health preparedness will determine whether outbreaks occur. Late last November, a young man walked into Renee Salas' emergency room with a circular rash spreading across his leg. Salas, an attending physician at Massachusetts General Hospital in Boston, treated him for possible Lyme disease from a tick bite—a diagnosis that bloodwork later confirmed. Field crews at the Connecticut Agricultural Experiment Station track the diversity and abundance of disease-carrying mosquitoes using traps baited with a yeast–hay infusion mixed with water. They also use traps that attract the mosquitoes using dry ice and light. Image credit: Connecticut Agricultural Experiment Station. " data-icon-position data-hide-link-title="0"> Field crews at the Connecticut Agricultural Experiment Station track the diversity and abundance of disease-carrying mosquitoes using traps baited with a yeast–hay infusion m...

Jock itch can usually be treated with nonprescription antifungal creams, lotions, or powders applied to the skin for two to four weeks. The nonprescription products available to treat ringworm include: Clotrimazole (Anti-Fungal Liquid, Fungicure) Miconazole (Aloe Vesta 2 in 1 Antifungal, Aloe Vesta Clear Antifungal, Azolen, Baza Antifungal, Critic-Aid Clear AF, Cruex Prescription Strength, DermaFungal, Desenex Jock Itch, Fungoid, Lagicam, Micaderm, Micatin, Mitrazol, Remedy Antifungal, Secura Antifungal) Terbinafine (Athlete's Foot Cream) Ketoconazole (Nizoral A-D) If you are not responding to over-the-counter medications, your doctor may prescribe something stronger, including these topical medications: Econazole (Ecoza) Oxiconazole (Oxistat) You may also be prescribed one of these oral medications: Fluconazole (Diflucan) Itraconazole (Onmel, Sporanox, Tolsura) Terbinafine (Lamisil) If you tend to get jock itch, you should continue to apply antifungal or drying powders after bathi...

ST. LOUIS — Now that the holiday season has concluded, perhaps you've noticed the warning signs of Alzheimer's disease or related dementia in aging family members.  George Grossberg, M.D., the Samuel W. Fordyce professor and director of geriatric psychiatry at Saint Louis University School of Medicine, said it is during family gatherings that caregivers often notice older adults 65 and over may be slipping cognitively. George Grossberg, M.D. (SLU file photo) Grossberg, a SLUCare physician, treats geriatric patients who suffer from a range of neurocognitive disorders, including Alzheimer's disease. He adds that African Americans are among those at the h...

JOHANNESBURG — The World Health Organization said authorities in Malawi have detected a case of polio in the southern African country's capital, another setback in continuing efforts to eradicate the highly infectious paralytic disease globally. In a statement on Friday, the U.N. health agency said officials had identified wild poliovirus disease in a young child in Lilongwe, the first time the wild virus has been detected on the African continent in five years. Although polio has been spreading in numerous African countries in recent years, those outbreaks were linked to viruses originally contained in vaccines, not to the wild virus. In very rare instances, the live virus in the oral polio vaccine can mutate into a version capable of causing epidemics, particularly in populations that haven't been immunized. WHO said lab tests showed the polio virus detected in Malawi is connected to the strain that has been spreading in Pakistan's Sindh province, where the disease r...

The long-range forecast for this spring includes a lot of sniffles. Two years of wearing masks, avoiding crowds, and trying not to catch COVID-19 had a welcome, if unplanned, byproduct: many people caught fewer colds and stomach bugs. But that could soon change. At the end of the month, Massachusetts will no longer require masks in schools and has dropped its recommendation that healthy vaccinated people wear masks indoors. Doctors say that means we should brace ourselves for the return of common infections many people have blissfully dodged for the past two years. "You will see a lot of anecdotal reports that the primary care offices and urgent cares are a little slammed," said Dr. Christina Hermos, a pediatric infectious disease specialist at UMass Memorial Children's Medical Center. Social measures to prevent the spread of the coronavirus have disrupted the transmission of many common pathogens around the world, most notably the flu. The flu virus barely made an appea...

Pneumonia is an illness we hear about often. There's a reason. It is a common disease that causes illness and death worldwide.    If it conjures up thoughts of severe illness, you are right. The symptoms vary from mild fever and cough to severe difficulty breathing and sepsis.    Pneumonia is the second leading cause of hospitalization after childbirth. It is the most common infectious cause of death.     "Pneumonia is an infection of the lungs that causes inflammation and may cause fluid build-up within the tiny sacs of the lungs," says Tammy Wichman, MD, Nebraska Medicine pulmonologist. "It can be caused by a virus, bacteria or a fungus. For healthy individuals, it usually isn't serious if treated early on. However, pneumonia can be quite serious for the elderly, people with weakened immune systems and young children." What causes pneumonia?  Bacterial pneumonia is commonly cau...

Submission history Received : 18 October 2019 Accepted : 27 January 2022 Published in print : 25 February 2022 Acknowledgments We thank all the members of the Di Santo laboratory for critical review of the manuscript, helpful discussions, and support. We thank G. Eberl (Institut Pasteur, France) and O. Mandelboim (Hebrew University, Israel) for providing Rorc GFP and Ncr1 GFP mice, respectively. We are indebted to S. Novault (Technology Core of the Center for Translational Science at Institut Pasteur, France) for cell sorting and M. Berard, R. Chennouf (Institut Pasteur, France, animal facilities), and M. Lecuit (Institut Pasteur, France) for support. We thank P. Bousso (Institut Pasteur, France) for critical comments on the manuscript. Funding: This work is supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), the Institut Pasteur, the Agence National pour le Recherche (ANR - ILC_MEMORY), and the European Research Council (ERC) under the E...

– First New Drug Application (NDA) submission targeted in Q4 2022 for lead program SB206 (berdazimer gel 10.3%) for molluscum contagiosum – – Ongoing advancement of priority development pipeline assets SB019, for the treatment of SARS-CoV-2, toward a Phase 1 study in 2022, and SB204, for the treatment of acne vulgaris, toward a registrational Phase 3 study in 2023 – – Company to host update conference call and webcast today at 8:30 a.m. ET – DURHAM, N.C., Feb. 22, 2022 (GLOBE NEWSWIRE) -- Novan, Inc. ("the Company" or "Novan") (Nasdaq: NOVN), today announced its financial and operating results for the year ended December 31, 2021 and provided a corporate update. The Company will host a conference call and webcast, today, February 22, 2022, at 8:30 a.m. ET (details below). "Over the course of 2021, we made significant progress across multiple fronts. With positive data in hand and the expertise we have amassed within our team, we are ex...