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Showing posts from June, 2024

Review of the Chest CT Differential Diagnosis of Ground-Glass Opacities in the COVID Era | Radiology

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pulmonary hypertension and left heart failure :: Article Creator Tectonic Bets On GPCR Heart Failure Drug Following Reverse Merger With Avrobio Tectonic Therapeutic has completed a reverse merger with Avrobio and will begin trading on the Nasdaq global market as Tectonic Therapeutic (ticker symbol 'TECX') on 21 June. Coinciding with the merger, the new company also completed a private placement of $130.7m with multiple US and European investors. Following the placement, Tectonic reported total cash reserves of $181m, before payment of final transaction-related expenses, which is expected to fund operations until mid-2027. As part of the merger, Avrobio enacted a 1-for-12 reverse stock split of its common shares, along with an issuance of a non-transferable contingent value right. Under that, shareholders will have the rights to cash payments received by Tectonic, if any, related to Avrobio's pre-transaction legacy assets. Avrobio...

Fatal Pulmonary Hypertension Associated with Short-Term Use of Fenfluramine and Phentermine | NEJM

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bacterial lung infection :: Article Creator Connecticut Woman Contracts Deadly Flesh-eating Infection Spreading At Rapid Levels In Japan A critically ill Connecticut woman has been treated for the same life-threatening, flesh-eating infection that is plaguing Japan.  The American patient was admitted to her local hospital after experiencing symptoms of vomiting, diarrhea, shortness of breath, elevated heart rate and low blood pressure.  Subsequent medical scans showed fluid buildup in the patient's lungs as well as respiratory and kidney failure.  Doctors maintain the woman's illness is the result of Streptococcal toxic shock syndrome (STSS), a lethal bacterial infection that has claimed the lives of 77 people in Japan this year alone.  STSS is stateside and causing concern among health care professionals. Puhhha – stock.Adobe.Com Scans revealed the Connecticut patient has fluid in her lungs. Lashkhidzetim – stock.Adobe.Com A...

Epidemiology, Pathogenesis, and Clinical Approach in Group 5 Pulmonary Hypertension

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scleroderma lungs :: Article Creator Understanding The Connection Between Lupus And The Lungs Cheryl Russell of Highland Beach, FL, doesn't indulge in what she calls "symptom chasing." After more than three decades with lupus, she refuses to head to the doctor every time she has joint pain or some other problem. "I learned early on that if I do that, I just end up going to specialist after specialist and having test after test, chasing symptoms that will disappear on their own," says Russell, who raised two now-grown children with her husband, Jake. "I let things have time to work themselves out before jumping on them."  Trouble began in June 2011 when she noticed she could no longer take a deep breath. She couldn't yawn, and sneezing felt weird. She didn't say anything to her husband, her children, or her doctor. By July, her breathing was worse, and her feet started to swell. Still Russell stayed silen...

Limited cutaneous systemic sclerosis (Scleroderma, CREST syndrome)

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right sided heart failure pulmonary hypertension :: Article Creator How To Conduct A Cardiovascular Assessment In Advanced Practice Read this article to learn how to conduct an advanced cardiovascular assessment to reveal heart abnormalities and associated symptoms and risk factors Abstract Cardiovascular disease remains one of the leading causes of death in developed countries, accounting for a quarter of UK deaths and morbidity. A cardiovascular assessment can reveal cardiac abnormalities and give an understanding of associated symptoms and risk factors to aid early diagnosis. This article, the sixth in a series on assessment and interpretation for advanced clinical practitioners, shows how to take an accurate history and complete a structured physical examination. This includes inspection, palpation and auscultation of the heart, arteries and veins. Citation: Coaten J, North Z (2024) How to conduct a cardiovascular assessment in advanc...