Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association



pulmonary arterial hypertension meaning :: Article Creator

What Is Pulmonary Hypertension?

If you have pulmonary hypertension, it means you have high blood pressure in your pulmonary arteries, the blood vessels that carry blood from the right side of your heart through your lungs.

PH happens when tiny arteries in your lungs get narrow.

This higher pressure makes your heart work harder to pump Over time, your heart gets weak and starts to fail.

You may not have any symptoms at first, but it's really important to get treated quickly. So tell your doctor right away if you're short of breath, tired, dizzy, or have fainting spells, or if you have chest pain, fast heartbeat, or swelling in your feet or legs.

There is no cure yet, but there are things that can and using oxygen. PH is different for everybody, so talk to your doctor to find the best treatment for you.

Remember, catch it early, and treat it quickly to slow it down and help you feel better. [MUSIC PLAYING] ","publisher":"WebMD Video"} ]]>

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SPEAKER

If you have pulmonary hypertension, it means you have high blood pressure in your pulmonary arteries, the blood vessels that carry blood from the right side of your heart through your lungs.

PH happens when tiny arteries in your lungs get narrow.

This higher pressure makes your heart work harder to pump Over time, your heart gets weak and starts to fail.

You may not have any symptoms at first, but it's really important to get treated quickly. So tell your doctor right away if you're short of breath, tired, dizzy, or have fainting spells, or if you have chest pain, fast heartbeat, or swelling in your feet or legs.

There is no cure yet, but there are things that can and using oxygen. PH is different for everybody, so talk to your doctor to find the best treatment for you.

Remember, catch it early, and treat it quickly to slow it down and help you feel better. [MUSIC PLAYING]


Study Highlights Pulmonary Artery Denervation As A Key Intervention For Pulmonary Hypertension

A recent publication in the International Journal of Cardiology, Pulmonary artery denervation in pulmonary hypertension: A comprehensive meta-analysis, has shed light on the potential of pulmonary artery denervation (PADN) as an innovative intervention for pulmonary hypertension (PH), a condition that places patients at risk for right heart failure and death. Co-authored by Dr. James Jenkins, a cardiologist at Ochsner Health, the study analyzed data from multiple clinical trials to assess the therapeutic and clinical impact of PADN in PH patients. 

PADN has emerged as a promising treatment, showing significant improvements in several key hemodynamic parameters and clinical outcomes. The meta-analysis, which reviewed 14 studies involving 372 patients, revealed that PADN could reduce metrics such as mean right atrial pressure (mRAP), mean pulmonary artery pressure (mPAP), and pulmonary vascular resistance (PVR). Simultaneously, it improved cardiac output (CO) and performance on the six-minute walk test (6MWT), highlighting its potential to enhance overall patient health. 

Despite these encouraging results, the authors emphasize the importance of conducting larger-scale clinical trials to confirm PADN's efficacy, establish its safety profile, and refine treatment protocols. Future research should also investigate the procedure's long-term effects on patient outcomes and quality of life. 

Pulmonary artery denervation has become a promising therapeutic intervention in the management of pulmonary hypertension. While our findings suggest a substantial role for PADN in treatment protocols, continuous research is crucial to fully understand its broader implications and long-term benefits." 

Dr. James Jenkins, cardiologist at Ochsner Health

As cardiovascular disease remains a leading cause of death globally, advancements like this represent critical progress in addressing life-threatening conditions. This study not only underscores the value of innovation in cardiology but also highlights the ongoing need for rigorous research to develop more effective and life-changing treatments for patients with complex conditions like pulmonary hypertension.

Source:

Journal reference:

Abouzid, M. R., et al. (2025). Pulmonary artery denervation in pulmonary hypertension: A comprehensive meta-analysis. International Journal of Cardiology. Doi.Org/10.1016/j.Ijcard.2025.133078.


Meta-analysis Reveals Pulmonary Artery Denervation As Promising Intervention For Pulmonary Hypertension

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