Poliomyelitis

systolic heart failure symptoms :: Article Creator Chronic Heart Failure - Heart Failure With Reduced Ejection Fraction Topic Review Introduction Chronic heart failure is a syndrome, not a specific disease, and occurs as a final common pathway in multiple disease states. The pathophysiology of chronic heart failure (HF) exists when either the left ventricle, the right ventricle, or both, require elevated filling pressures to maintain cardiac output. The neurohormonal responses to impaired cardiac function constitute a negative feedback cycle that is an integral part of the HF syndrome and, to date, blockade of that cycle is the most effective pharmacologic approach to management. HF can be due to the following: Systolic dysfunction with reduced ejection fraction - HFrEF Diastolic dysfunction abnormal relaxation or impaired filling with preserved ejection fraction - HFpEF Valvular heart disease ...

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pregnancy blood pressure chart :: Article Creator Normal Blood Pressure In Pregnancy May Still Signal Future Hypertension Risk A new study has found that some women who maintain blood pressure levels within the clinically normal range during pregnancy may still be at significantly higher risk of developing high blood pressure within five years of giving birth—especially if their blood pressure does not drop during the second trimester, as is typical in healthy pregnancies. The research, published in the Journal of the American College of Cardiology: Advances, shows that about 12% of pregnant women fall into this overlooked risk category. These women would not be flagged under current medical guidelines, as their blood pressure remains below the standard thresholds for concern. Yet, their risk of developing chronic hypertension after pregnancy was found to be nearly five times higher than women whose blood pressure followed the expected healt...

systolic pressure in pulmonary artery :: Article Creator PH Risk Grows Over Time With COA, Or Narrowing Of Aorta: Study People with coarctation of aorta, or COA — a condition marked by narrowing where the body's largest blood vessel connects to the heart — are at high risk of developing pulmonary hypertension (PH), and this risk increases as time goes on, a study showed. The data also showed that PH progression is associated with heightened mortality risk among people with COA, emphasizing a need for better treatment strategies in this patient population, according to the researchers. "These findings underscore the clinical importance of [PH] in COA and [support] the need for new strategies for prevention and treatment of [heart conditions that increase PH risk]," the researchers wrote, noting that new therapies "should, in turn, slow the pace of [PH] progression in this [patient] population." The study, "Tempora...

scleroderma hypertension :: Article Creator Bob Saget 'Wanted People To Understand How Bad' Scleroderma Can Be: 'This Was His Life's Work' Bob Saget was a tireless champion for causes of all kinds, but none were as close to his heart as scleroderma research. The beloved comedian — who died Sunday at age 65 — had spent the last 25 years "committed" to raising awareness of scleroderma, the rare autoimmune disorder that his older sister Gay died from in 1996. "He was very close to his sister, and I think part of his long-term commitment was because he was really disappointed with the understanding of her condition," Luke Evnin, the chairman of the Scleroderma Research Foundation and co-board member with Saget, tells PEOPLE. "He was very disappointed with the sophistication of the tools that were available at the time to alleviate or change the course of her disease, and even just ease her suffering a...

cystic fibrosis exacerbation :: Article Creator Cystic Fibrosis Foundation To Fund Development Of Breath Test For Pseudomonas Infections The UK Health Security Agency (HSA) today published a new priority pathogens tool—outlining pathogen families that pose the biggest risk to public health—to help support funding of research and development into new diagnostics, vaccines, and treatments. NIAID/Flickr cc The list contains 24 pathogen families, providing rankings of high, moderate, or low regarding pandemic and epidemic potential. The HSA said its scientists took into account transmission routes and disease severity. In a statement, the agency said the ratings aren't intended as a detailed threat assessment and don't indicate which pathogen is most likely to trigger then next pandemic, but rather which ones require increased scientific investments and study. The rankings also highlight which pathogens need increased diagnostics and vacci...