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Chronic Kidney Disease (CKD): Practice Essentials, Pathophysiology, Etiology

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ipf lung disease :: Article Creator Endeavor Pulls In $132M To Back Cancer, Lung Disease Drugs Endeavor BioMedicines has raised $132.5 million in a Series C round designed to advance its two experimental medicines deeper into clinical testing, the San Diego company announced Wednesday. The round was led by AyurMaya, an affiliate of investment firm Matrix Capital Management. Originally, the company's financing target was between $75 million and $100 million, according to CEO John Hood. But Endeavor upped its expectations after reaching out to investors late last year. Hood and his team found strong interest in a biotech with two drugs in early- and mid-stage testing, suggestive of the current investment climate favoring more mature drug startups. The company revealed positive Phase 2 study results in January while putting its funding together. "We got the luxury of raising on really good clinical data for a disease with high unmet need...

Diabetes, Heart Disease, & Stroke - NIDDK

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bronchitis lungs :: Article Creator Horrifying Video Reveals How Smoking Leaves Your Lungs Black, Shrivelled And 'steeped In Tar' WE'RE constantly warned about how smoking can destroy our lungs and health. There are certain outward signs we've come to recognise as consequences of the habit: a smoker's perpetual hacking cough, sagging skin, yellowing teeth. 1 A video shared to Instagram laid bare how radically cigarettes can affect your lung function Now a horrifying video has laid bare just how much damage cigarettes can cause to the inside of your body, showing how smoking can leave the lungs blackened, shrivelled and coated in tar. It comes as MPs prepare to vote on legislation that aims to create a "smokefree generation" by raising the age of sale for tobacco in England by one year every year. If the legislation comes into effect, it would mean children turning 15 this year or younger will never be a...

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology ...

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terminal heart failure :: Article Creator Doctors Combined A Heart Pump And Pig Kidney Transplant In Breakthrough Surgery A 54-year-old New Jersey woman has become the second living person to receive a genetically engineered pig kidney. The surgery, carried out at NYU Langone Health on April 12, also involved transplanting the pig's thymus gland to help prevent rejection. The patient, Lisa Pisano, had a mechanical heart pump implanted days before getting the transplant. She was facing heart failure and end-stage kidney disease and wasn't eligible for a human organ transplant because of several other medical conditions. Her medical team says she's recovering well. "I feel fantastic," Pisano said from her hospital bed over Zoom during a press conference on Wednesday. "When this opportunity came, I said, 'I'm gonna take advantage of it.'" It's the first instance of a patient with a mechanical hear...

Congenital heart disease in adults - Symptoms and causes

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lung rads 1.1 :: Article Creator Mereo BioPharma Provides Regulatory Updates On Alvelestat For The Treatment Of Alpha-1-Antitrypsin Deficiency-Associated Lung Disease Mereo BioPharma Group plc Clear path forward with proposed single Phase 3 study evaluating alvelestat at the 240 mg dose level versus placebo at 12-18 months for potential full approval in both the U.S. And EU No additional confirmatory study required Company to host conference call today at 8:30am ET LONDON, March 21, 2023 (GLOBE NEWSWIRE) -- Mereo BioPharma Group plc (NASDAQ: MREO) (Mereo or the Company), a clinical-stage biopharmaceutical company focused on rare diseases, today announced regulatory feedback following recent end-of-Phase 2 meetings with the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) related to its alvelestat program for the treatment of alpha-1-antitrypsin deficiency-associated lung disease (AATD-LD). Based on clear ...

Congenital Heart Disease: Symptoms & Treatment

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shore pulmonary :: Article Creator He Didn't Have A Pulse For More Than 5 Minutes But Still Survived Near-drowning NEW SMYRNA BEACH, Fla. (WESH) - On the central east coast of Florida, a story of survival happened on New Smyrna Beach. An unconscious man was rescued from the ocean last month, and it was caught on camera. A visit to the beach almost ended a 21-year old's life. "The first thing he said is he's never going to the beach again," said Deputy Stan Manhart with Volusia County Sheriff's Office. Manhart was one of the first responders on the scene the day Felipe Ribeiro DeSouza got caught in a riptide. Several people were rescued March 30, Ribeiro DeSouza was the only one who was unresponsive. Two boogie boarders pulled him out of the water. They put him on their board until lifeguard Dalton Smith reached them. "We just let him know that they needed to hold his head up above water. And we just swa...

Congenital Heart Disease: Symptoms & Treatment

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acute pulmonary heart disease :: Article Creator Lung Disease Patients More Likely To Develop Heart Disease Independent Of Any Risk Factors Patients with lung disease are more likely to develop heart disease independent of any risk factors, according to new research. A new study published in Orphanet Journal of Rare Diseases looked at patients who have a rare genetic condition called Alpha-1 antitrypsin deficiency (AATD) which causes lung disease similar to COPD independently of any risk factors such as smoking or age. More than 220 patients with AATD were recruited to the study alongside patients with COPD, and a control non lung disease population; and all were assessed for present cardiovascular disease (CVD) and recognized risk factors, including assessment of vascular stiffness known to increase risk for future events. Patients were then tracked for four years to see whether they developed CVD. The patients with the rare genetic conditi...