Bacterial biofilm (BF) formation in patients with malignancy | IDR - Dove Medical Press
Introduction Double J ureteral stent, frequently used for indwelling ureter, can effectively relieve ureteral obstruction and prevent ureteral stenosis. 1 Consequently, preoperative or intraoperative indwelling double J stent is a common measure to prevent ureteral injury 2 as well as postoperative upper urinary tract obstruction due to surgery or metastasis of tumor in patients with malignant tumors, especially gynecological and urinary malignant tumors. 3 However, its therapeutic effect is undermined by complications, such as urinary tract infection and urinary sepsis in severe cases, which threatens the life and health of patients. 4 It has been confirmed by relevant research that bacteria biofilm (BF) formation, membrane-like substances formed by bacteria adhering to the surface, can enable bacteria to develop drug resistance against antimicrobial agents. 5 As a result, it is considered that the formation of BF may be a key contributory factor to the relapse and intractabi...