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pulmonary inflammation :: Article Creator QCT Textures In COPD May Show Lung Inflammation Distribution, Disease Burden Quantitative computed tomography (QCT) textures may provide imaging evidence of the spatial heterogeneity of lung inflammation and disease burden in patients with chronic obstructive pulmonary disease (COPD), according to study findings published in Chest. Researchers analyzed data from the SPIROMICS and COPDGene cohort studies (ClinicalTrials.Gov Identifiers, NCT01969344 and NCT00608764, respectively) to determine whether local textures of the bronchovascular bundles (BVB) and the surrounding regions, quantified by the adaptive multiple feature method, are associated with systemic inflammation, impaired lung function, and all-cause mortality, independent of CT-based emphysema and airway wall thickening. SPIROMICS participants had high-resolution chest CT scans at total lung capacity (TLC) and residual volume. COPDGene enrolled ...