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reverse hypertension :: Article Creator Uncontrolled Hypertension: What Does This Mean? Uncontrolled hypertension means an individual has blood pressure above 140/90 mm Hg. It can refer to when high blood pressure has been untreated or when treatments have been ineffective. According to the World Health Organization, approximately 21% of adults have high blood pressure that's not controlled. Although these individuals may not have noticeable symptoms as a result of their uncontrolled hypertension, their high blood pressure can present a serious risk of other health conditions like stroke, heart attack, and kidney disease. If you or someone you care about has recently received a diagnosis of high blood pressure, you may have a lot of questions. This article will explain what uncontrolled hypertension means, how it differs from other hypertension types, and what you may consider consulting your care team about when it comes to treating...

pulmonary valve insufficiency :: Article Creator First Of Its Kind 'J-Valve' Surgery Performed At Christ Hospital A first-of-its-kind surgery is being performed as part of a clinical trial at The Lindner Research Center.The minimally invasive surgery is designed to treat severe native aortic regurgitation and AR-dominant mixed aortic valve disease in patients.The successful procedure was done by Dr. Dean Kereiakes, Dr. Santiago Garcia and the team at The Lindner Research Center at The Christ Hospital Health Network earlier this month.Enrollment for the early feasibility study using the device was announced through a partnership between the Christ Hospital Heart & Vascular Institute and Genesis MedTech, a medical device company. The J-Valve TF System, which was developed by JC Medical, is regarded as a valve that addresses unmet clinical need and has potential to help many, as described by Dr. Garcia, principle investigator for the study at...

accredo pulmonary hypertension :: Article Creator Medications For Pulmonary Arterial Hypertension Medically reviewed by Femi Aremu, PharmD Pulmonary hypertension (PH) can be challenging for healthcare professionals to diagnose because of its vague symptoms, such as fatigue and shortness of breath. These symptoms, which may be mild initially, can sometimes lead to a misdiagnosis, such as asthma or heart failure. In fact, a recent study suggests that board-certified physicians specializing in heart and lung conditions may correctly suspect PH less than 50% of the time. Related to PH, healthcare providers may also deal with the diagnosis and treatment of pulmonary arterial hypertension (PAH), a specific type of PH characterized by hypertension (high blood pressure) in the pulmonary arteries. ADVERTISEMENT Advertisement Because PAH can be severe and often challenging to treat, it can lead to severe short- and long-term health challenge...

acute pulmonary insufficiency :: Article Creator Pembrolizumab-Induced Myasthenia Gravis Case Points To Need For Treatment Standardization This case report details an incident of pembrolizumab-induced myasthenia gravis in an elderly male patient being treated for urothelial cell bladder cancer. Researchers are calling for further investigation of the adverse effects (AEs) of pembrolizumab and other members of its drug class following a case of pembrolizumab-induced myasthenia gravis in an 87-year-old male patient being treated for urothelial cell bladder cancer.1 Doing so, they believe, holds potential to help identify future patients who may have a high risk of poor outcomes with these medications. "It is evident that although immune checkpoint inhibitors have provided effective treatment for devastating diseases, they also present the risk of untoward AEs," the study authors published in Cureus. "This case highlights the importa...

ventricular diastolic dysfunction :: Article Creator Q&A With Ming Hui Chen, MD: Changes In Diastolic Function After HSCT In Children Although changes in systolic function over time after hematopoietic stem cell transplantation (HSCT) have been well documented, echocardiographic data on the rate of changes in diastolic function prior to the development of clinically overt disease is lacking in post-HSCT patients, including children.1  The Bottom Line "Our study findings underscore that it's not the systolic function, but the diastolic function that first becomes abnormal in these patients. The projected time course of diastolic and systolic dysfunction may be helpful for clinicians in tailoring their care for higher-risk patients."—Ming Hui Chen, MD, MMSc, Harvard University, and Boston Children's Hospital Ming Hui Chen, MD, MMSc and colleagues, in a previous study conducted at the Boston Children's Hospital/Dana-Far...