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bmpr2 mutation pulmonary hypertension :: Article Creator What To Know About Primary Pulmonary Hypertension Primary pulmonary hypertension, also called pulmonary arterial hypertension (PAH), occurs when arteries in the lungs become thick and narrow. This raises blood pressure in the lungs by restricting blood flow. The condition also causes a person's heart to work harder to pump blood through the narrowed arteries. Eventually, a person's heart may lose the ability to effectively pump blood throughout the body. PAH is a type of pulmonary hypertension, or high blood pressure in the lungs. Additionally, it is a rare, progressive disorder. This means it worsens over time. Treatments typically focus on managing symptoms and improving quality of life. The condition most commonly affects females between the ages of 30 and 60, reports the American Lung Association. Healthcare professionals diagnose about 500–1,000 new cases of PAH in the U...