Poliomyelitis

*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. In a recent study posted to the bioRxiv* preprint server, researchers examine the interactions between the influenza A virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a co-infected host, as well as the interactions between these viruses and the host using human airway epithelium cultures from co-exposed hosts. Study:  Counterintuitive effect of antiviral therapy on influenza A-SARS-CoV-2 coinfection due to viral interference . Image Credit: Artbox / Shutterstock.com Background The circulation of emergent SARS-CoV-2 variants, the recent resurgence of the influenza A virus, and the winter seasonality of the two viruses have increased the probability of co-infections. Although co-inf...

Source: National Association of State Departments of Agriculture (NASDA) news release At the National Association of State Departments of Agriculture Winter Policy Conference today, NASDA, the U.S. Department of Agriculture (USDA), National Pork Board (NPB) and National Pork Producers Council (NPPC) announced a new partnership to enhance coordination and preparedness to prevent and protect the United States from African Swine Fever (ASF), a deadly pig disease that could cripple the entire agricultural sector with long-lasting ramifications for the economic viability of U.S. livestock production. The enhanced partnership between these four entities will allow for the most effective harmonization of federal and state response plans to enable producers to prevent, plan and recover from African swine fever outbreaks, as well as encourage industry preparation for future outbreaks and disease response in other livestock sectors, which fosters rural food security and public confidence in ...

In this article GIS AN VIR HD WMT Follow your favorite stocks CREATE FREE ACCOUNT The Walmart logo is displayed outside their store near Bloomsburg. Paul Weaver | Lightrocket | Getty Images Check out the companies making the biggest moves in premarket trading: Walmart — Walmart shares fell about 4% before the bell after sharing a cautious outlook for the year as consumers trade down and purchase fewer discretionary items. The move in shares came even after the retail giant beat expectations on both the top and bottom lines for the holiday quarter. Home Depot — The retail stock dropped 4% in premarket trading after Home Depot's fourth-quarter report showed lighter-than-expected sales. Home Depot reported $3.30 in earnings per share on $35.83 billion of revenue. Analysts surveyed by Refinitiv were expecting earnings of $3.28 per share on $35.97 billion in revenue. Home Depot also said it expected sales to be flat in the new fiscal year. Vir Biotechnology — The immunology company j...

Prophylactic HPV vaccination and anal cancer in Thailand. Image Credit: Shutterstock/CNK02 On December 20, 2022, the World Health Organization (WHO) updated its recommendations for cervical cancer vaccines in a bid to boost vaccination coverage. The WHO now says that a one-dose schedule for girls ages 9–14 years adequately protects against human papillomavirus (HPV), and more specifically, the HPV 16 and HPV 18 strains. The insights and amendments came following findings from a meeting held by WHO's independent expert advisory group in April 2022. Several cervical cancer vaccines are currently approved, including Merck's nonavalent vaccine Gardasil 9 and GSK's bivalent vaccine Cervarix. In September 2022, th...

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Placentas helping treat dry eyes quickly A Houston-area woman who suffers from dry eye disease for decades talks about how a new treatment quickly stopped her pain thanks to amniotic tissue from new mothers who donate their placenta after their baby is born. THE WOODLANDS, Texas - Gritty, dry, itchy eyes can feel miserable, but there is now a new state-of-the-art treatment that is repairing the problem in record time. A doctor in The Woodlands believes it's one of the biggest advancements in treating not only dry eye disease, but many other problems affecting the cornea. MORE: Free health care in Houston leads to free education plus a job Kiki Koymarianos suffered for decades with painful, dry eyes. It even affected her eyesight. "After the afternoon, I will start getting tired, itching, burning sensation, all different kinds of things. It sounds and feels miserable," says Kiki. Kiki is certainly not alone. Dry eye disease is a chronic, inflammatory condition t...

Onychomycosis Pipeline Insight As per Global Insight services' assessment, about 13 prominent pharma and biotech giants are working on 13 drugs in the Onychomycosis - pipeline landscape globally. Onychomycosis Pipeline Insight, 2023" report by Global Insight Services provides a comprehensive analysis of the ongoing clinical development activities and growth prospect. Download PDF Sample Pages to Get an in-depth Assessment of the Emerging Therapies and Key Companies: https://www.globalinsightservices.com/request-sample/GIS31243 Onychomycosis is a fungal infection of the nail plate, nail bed, or both. Infection may be distal subungual, with nail thickening and yellowing and accumulation of keratin and debris underneath the nail, proximal subungual or white superficial with spreading of chalky white scale beneath the nail surface. Onychomycosis is caused by 3 main classes of fungi: dermatophytes, yeasts, and non-dermatophyte molds. Dermatophytes are by far the most common cause o...

In the 1930s, the first coronavirus was isolated in North Dakota, USA, from poultry suffering from a respiratory disease called infectious bronchitis. Infectious bronchitis (IB) is a highly contagious and acute disease of poultry caused by the Infectious Bronchitis Virus (IBV). In the 1930s, the first coronavirus was isolated in North Dakota, USA, from poultry suffering from a respiratory disease called infectious bronchitis. Particularly in high-density commercial manufacturing facilities, IBV continues to be a global concern for the poultry industry. With a high mortality rate (25–60%) in infected flocks, IBV has a significant economic impact. Chickens of all ages (young, layer, and broiler) are susceptible, with younger birds displaying more serious clinical signs than older ones. IBV infection is regarded as the second most threatening poultry illness in the world. Etiology Coronaviruses are the largest RNA viruses. They&nb...

What Is Ecoza? Ecoze (econazole) is an azole antifungal topical medication used to treat certain fungal infections of the skin. Econazole blocks a fungal protein called cytochrome P-450-mediated 14 alpha-lanosterol demethylase enzyme. By inhibiting this fungal protein, econazole prevents lanosterol—a type of steroid—from converting to ergosterol . Ergosterol is important in forming the fungal cell wall. So, econazole works by interfering with the structure of the fungal cell wall. Econazole is available as a topical cream (generic econazole) or as a foam (under the brand name Ecoza). It can be used to treat infections such as: Drug Facts Generic name :   Econazole Brand name(s) : Ecoza Drug availability : Prescription Administration route :   Topical Therapeutic classification :   Antifungal Available generically :   Yes Controlled substance :   N/A Active ingredient :   Econazole...

News of the week Locally, COVID cases continue to climb slowly. The county recorded 464 active cases as of Tuesday's update from the Santa Cruz County Health Services Agency . That's 63 more than last Monday. No new deaths were reported locally, keeping the county's pandemic death toll at 276. Hospitalizations are down across the country according to the Centers for Disease Control . Local transmission, though, hasn't changed. Santa Cruz and its neighboring counties have remained in the "substantial" tier of community transmission , which means that they are all recording more than 50 cases per 100,000 people. Currently, Santa Cruz county is seeing 92 cases per 100,000 people — up from 11 last week. Gov. Gavin Newsom is expected to end California's COVID state of emergency on Feb. 28 . That will mean a number of changes to the services we have grown accustomed to over the p...

Colonies of Escherichia coli isolated from a patient's blood. Credit: Rodolfo Parulan Jr/Getty Images Advertisement Sign up for Scientific American ’s free newsletters. " data-newsletterpromo_article-image="https://static.scientificamerican.com/sciam/cache/file/4641809D-B8F1-41A3-9E5A87C21ADB2FD8_source.png" data-newsletterpromo_article-button-text="Sign Up" data-newsletterpromo_article-button-link="https://www.scientificamerican.com/page/newsletter-sign-up/?origincode=2018_sciam_ArticlePromo_NewsletterSignUp" name="articleBody" itemprop="articleBody"> About half of women and more than one in 10 men will get a urinary tract infection (UTI) in their lifetime, with many people experiencing recurrent UTIs. These common bacterial infections, which can lead to painful urination, have been easily treated and cured with antibiotics for decades. But as a result of antibiotic resistance—when bacteria becom...