Poliomyelitis

War on cancer: Duke spinout pursues revolutionary treatment using polio vaccine - WRAL Tech Wire War on cancer: Duke spinout pursues revolutionary treatment using polio vaccine - WRAL Tech Wire Posted: 10 Dec 2020 12:00 AM PST DURHAM – A Duke University spinout has developed an immune-boosting technology using variations of the polio vaccine that does more than wipe out a targeted solid tumor. "It clears the body of others as well, not just where it's injected," said Matt Stober, president and CEO of RTP-based Istari Oncology . Istari's primary technology platform is the Polio Virus Sabin-Rhinovirus Poliovirus (PVSRIPO). The results from multiple trials and preclinical research streams indicate that PVSRIPO has the potential to treat a variety of solid tumors that were previously thought of as untreatable. Although the company began by focusing on the deadly brain cancer glioblastoma multiform, a treatment in Phase I...

Just give us the vaccines, WHO pleads, as poor countries go wanting - Reuters Just give us the vaccines, WHO pleads, as poor countries go wanting - Reuters Posted: 25 Jun 2021 06:08 PM PDT World Health Organization (WHO) Director General Tedros Adhanom Ghebreyesus speaks during a bilateral meeting with Swiss Interior and Health Minister Alain Berset on the sidelines of the opening of the 74th World Health Assembly at the WHO headquarters, in Geneva, Switzerland May 24, 2021. Laurent Gillieron/Pool via REUTERS GENEVA, June 25 (Reuters) - Rich countries are opening up societies and vaccinating young people who are not at great risk from COVID-19, while the poorest countries cruelly lack doses, the World Health Organization said on Friday, condemning a global failure. The situation in Africa, where new infections and deaths jumped by nearly 40% last week compared to the previous week, is "so dangerous" as the Delta variant spreads g...

Scientists have used genetic engineering to develop a vaccine that offers full protection against malaria in animal studies. Researchers and health officials have long sought a vaccine against malaria, which in 2019 sickened an estimated 229 million people and caused 409,000 deaths globally. Once infected, many people suffer recurring bouts that undermine their health and quality of life. Pregnant women, children and travelers with no previous exposure to the malaria parasites transmitted by mosquitoes are at highest risk of severe disease. Since United States military forces are also at risk when deployed to areas where malaria is endemic, its control has long been a priority for the Department of Defense. The novel vaccine based on mRNA technology was developed by scientists from the Walter Reed Army Institute of Research (WRAIR) and Naval Medical Research Center, in partnership with researchers from the University of Pennsylvania and Acuitas Therapeutics. Researchers used mRNA t...

From smallpox to polio, vaccine rollouts have always had doubters. But they work in the end - The Conversation AU From smallpox to polio, vaccine rollouts have always had doubters. But they work in the end - The Conversation AU Posted: 07 Jun 2021 12:00 AM PDT In 2019, before COVID-19, the World Health Organization (WHO) identified vaccine hesitancy as one of the top ten greatest threats to global health . Every year, vaccination saves around 4-5 million lives, although a further 1.5 million lives could be saved annually with improved global vaccine coverage . Now, we are seeing a new round of vaccine hesitancy in some corners as the COVID vaccine is rolled out. But that's nothing new. Anti-vaccination movements have existed for as long as vaccination. Read more: Coronavirus: the road to vaccine roll-out is always bumpy, as 20th-century pandemics show From cowpox came the smallpox vaccine The first modern vaccine was the small...

Pediatric Hexavalent Combination Vaccine Vaxelis Now Available - Clinical Advisor Pediatric Hexavalent Combination Vaccine Vaxelis Now Available - Clinical Advisor Posted: 11 Jun 2021 07:48 AM PDT Vaxelis™ (diphtheria and tetanus toxoids and acellular pertussis, inactivated poliovirus, Haemophilus b conjugate and hepatitis B vaccine) is now available in the United States.  Vaxelis is the first hexavalent combination vaccine indicated for active immunization to prevent diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, and invasive disease due to Haemophilus influenzae type b. The vaccine is approved for use as a 3-dose series in children from 6 weeks through 4 years of age (prior to the 5th birthday). The 3-dose series consists of a 0.5 mL intramuscular injection administered at 2, 4, and 6 months of age. Vaxelis has been included as a combination vaccine option in the Centers for Disease Control and Prevention's (CDC) reco...

Prineville Boy selected as first poster child for March of Dimes - Pamplin Media Group Prineville Boy selected as first poster child for March of Dimes - Pamplin Media Group Posted: 19 Jun 2021 12:00 AM PDT Donald Anderson had contracted polio at age 5 in 1943 and became the 'darling' of the Shriner's Hospital Franklin D. Roosevelt, an adult victim of polio, founded the National Foundation for Infantile Paralysis, which he later renamed the March of Dimes Foundation, on Jan. 3, 1938. It became known as the March of Dimes because an appeal was made by Roosevelt for the general public to help fund research. A celebrity urged the public to send dimes to the White House. The public responded by sending 2,680,000 dimes and thousands of dollars in donations. Research eventually led to a vaccination for polio being developed. After Roosevelt's death, the March of Dimes Foundation decided to have a national effort for a post...

Polio: When vaccines and reappearance were just as difficult | Lifestyle - Pennsylvanianewstoday.com Polio: When vaccines and reappearance were just as difficult | Lifestyle - Pennsylvanianewstoday.com Posted: 14 Jun 2021 09:23 AM PDT Cincinnati (AP) — The COVID-19 pandemic and the distribution of vaccines to prevent it surface unforgettable memories for Americans who lived in earlier times when the country seemed to have been infected by the virus for a long time. Treatment or prevention. They were children at the time. They had friends and classmates who were tied up in wheelchairs or dragged in orthoses. Some have gone to the hospital to use the iron lungs they need to breathe. Some people didn't go home. Now they are elderly. Again, they find themselves in one of the most devastating age groups, as they did in polio childhood. They share their memories with today's young people as a hopeful lesson for their emergence fro...

Can people vaccinated against COVID-19 still spread the virus? What we know so far - WJW FOX 8 News Cleveland Can people vaccinated against COVID-19 still spread the virus? What we know so far - WJW FOX 8 News Cleveland Posted: 30 May 2021 12:00 AM PDT ** Related Video Above: Getting COVID-19 vaccine is more complicated for teens with anti-vax parents ** (THE CONVERSATION) When the U.S. Centers for Disease Control and Prevention  changed its guidelines about mask-wearing  on May 13, 2021, plenty of Americans were left a little confused. Now anyone who is fully vaccinated can participate in indoor and outdoor activities, large or small, without wearing a mask or physical distancing. Anthony Fauci, chief medical adviser to President Biden, said the new guideline is " based on the evolution of the science " and "serves as an incentive" for the  almost two-thirds of Americans  who are not yet fully vaccinated to go ahead an...