Poliomyelitis

Measuring Neurological Impact of Polio Proves Useful in SMA, Study... - SMA News Today Measuring Neurological Impact of Polio Proves Useful in SMA, Study... - SMA News Today Posted: 11 Dec 2020 12:00 AM PST Researchers have found changes in the electrical activity between the brain and muscles in adults who had childhood polio — an infection that affects the same motor neurons as those impacted in people with spinal muscular atrophy (SMA), a study reported.  The inexpensive and non-invasive technique used to measure these changes can also be employed to find the neurological networks responsible for daily movements in SMA, the researchers said. Moreover, the technique can further be used as a biomarker to assess the impact of disease-modifying therapies.  The study, " Altered supraspinal motor networks in survivors of poliomyelitis: A cortico-muscular coherence study ," was published in the journal Clinical Neurophysiology...

Potential ALS Marker Found in Polio-related Study of Brain Motor Network - ALS News Today Potential ALS Marker Found in Polio-related Study of Brain Motor Network - ALS News Today Posted: 01 Dec 2020 12:00 AM PST New research into the motor networks of polio survivors shows the brain may "rewire" itself in neurological diseases, leading to a reorganization that also may serve as a potential biomarker of amyotrophic lateral sclerosis (ALS) and other motor neuron disorders, a study reports.  Published in the journal Clinical Neurophysiology , the study, by researchers at Trinity College Dublin , is titled " Altered Supraspinal Motor Networks in Survivors of Poliomyelitis: A Cortico-Muscular Coherence Study . " "This study is especially interesting because it shows that advanced methods in neurophysiology and neural signal analysis can help to unravel new aspects of how different diseases disrupt our ...

Nonagenarians recall living with polio scare, how that compares with COVID-19 - Cadillac News Nonagenarians recall living with polio scare, how that compares with COVID-19 - Cadillac News Posted: 27 Dec 2020 09:00 PM PST The last time Americans waited this anxiously for a new vaccine was more than six decades ago, and even then, people had mixed feelings about both the disease and the cure. George Gruenberg, 92, was about 4 or 5 years old at the time he developed polio, which crippled one of his legs and made it very difficult to move. "My mother used to help drag me around the house,' Gruenberg said. "I had trouble sleeping because it hurt so bad. I had leg aches at night and couldn't walk. I had to use my other leg to get around.' As a result of his affliction, Gruenberg had to postpone a year of his schooling and when he returned, he completed kindergarten and first grade in a single year to catch up ...

1962 polio vaccine drive relevant for today's push to immunize - NET Nebraska 1962 polio vaccine drive relevant for today's push to immunize - NET Nebraska Posted: 10 Dec 2020 12:00 AM PST As the U.S. prepares for one of the largest vaccination efforts in history, it's worth looking back sixty years ago, when the country worked to eliminate another deadly virus: polio. One of the most successful campaigns came to life in an Omaha, Nebraska TV studio. Wellbee was the U.S. Communicable Disease Center's symbol of public health. (CDC Archives) KMTV Sabin Oral Sunday studio broadcast. Nurses prepare to administer vaccine at Omaha Dodgers baseball game on KMTV (History Nebraska archives) In the black and white film shot at Omaha's KMTV studios in 1962, the event labeled  Sabin Oral Sunday  (SOS) looks like a combination of a telethon and election night. Local night club acts and polka bands shared air ti...

Potential ALS Marker Found in Polio-related Study of Brain Motor Network - ALS News Today Potential ALS Marker Found in Polio-related Study of Brain Motor Network - ALS News Today Posted: 01 Dec 2020 12:00 AM PST New research into the motor networks of polio survivors shows the brain may "rewire" itself in neurological diseases, leading to a reorganization that also may serve as a potential biomarker of amyotrophic lateral sclerosis (ALS) and other motor neuron disorders, a study reports.  Published in the journal Clinical Neurophysiology , the study, by researchers at Trinity College Dublin , is titled " Altered Supraspinal Motor Networks in Survivors of Poliomyelitis: A Cortico-Muscular Coherence Study . " "This study is especially interesting because it shows that advanced methods in neurophysiology and neural signal analysis can help to unravel new aspects of how different diseases disrupt our ...

New immunotherapy piggybacks off polio vaccine to treat cancer - The Science Board New immunotherapy piggybacks off polio vaccine to treat cancer - The Science Board Posted: 17 Dec 2020 10:51 AM PST By Samantha Black, PhD, The Science Advisory Board editor in chief As if we needed another reason to get vaccinated, researchers have developed a technology that leverages the polio vaccine to help treat cancer for those who develop the disease later in life. The technology, conceived at Duke University and developed by Istari Oncology, uses antigens produced by the polio vaccine to trigger the immune system to eat away at targeted cancer cells. Matt Stober, president and CEO of Istari Oncology. Istari is a company that was spun out of Duke University Tisch Brain Tumor Center and is focused on developing novel immunotherapies for solid tumors, according to Matthew Stober, president and CEO of Istari and Dr. Garrett Nichols, chief medical o...

Dr. Roach: No reason this West Nile patient should skip the flu vaccine - The Detroit News Dr. Roach: No reason this West Nile patient should skip the flu vaccine - The Detroit News Posted: 18 Dec 2020 12:02 PM PST Keith Roach, To Your Health Published 3:00 p.m. ET Dec. 18, 2020 Dear Dr. Roach: I am a paraplegic due to complications from the West Nile virus. I am getting conflicting information from my health care providers concerning flu shots. My primary care doctor says that the flu shots are contraindicated for West Nile victims; my pharmacist says the vaccinations are OK; and my hematologist is unsure. I would like to get a flu shot and a vaccination for COVID-19 when available. Please give me a definite answer. — P.H.L. Dear P.H.L.: West Nile virus was relatively unknown in the U.S. until 1999, when an outbreak occurred in New York, but WNV now has been found in all the continental states and Canadian provinces. It is an a...