Edema formation in congestive heart failure and the underlying mechanisms
pulmonary hypertension and emphysema :: Article Creator Long-Term Ventilation Linked To Improved Survival In COPD-OSA Patients A RECENT study highlights the potential survival benefits of long-term positive airway pressure (PAP) therapy for patients with both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA). The study compared outcomes for patients hospitalised with acute hypercapnic respiratory failure who had COPD alone versus those with COPD-OSA overlap syndrome (OVS), revealing a trend toward lower mortality among OVS patients, especially those discharged on home PAP therapy. The retrospective cohort study followed 168 patients, including 124 with COPD alone and 44 with OVS, over a median period of 20.6 months. All patients required non-invasive ventilation during their hospitalisation but only continued PAP therapy if prescribed upon discharge. At admission, the two groups had similar blood pH and carbon dioxide